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Building upon this initial VP64 fusion, the combinatory fusion of VP64, p65, and Rta (VPR) to the C-terminus of dCas9 produces significantly higher transcriptional activation, with an effect size ranging from 22-fold to 320-fold greater than VP64 alone [68]
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Size:500 ml
doi: 10.3390/tropicalmed3030081 142 PontesLADias-NetoERabelloA
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