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thus, further clinical research is essential to inform anticoagulation decisions for these patients and to evaluate the safety profiles of DOACs in comparison to warfarin
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Since antioxidant defense systems become severely impaired upon MDMA exposure, administration of small molecule antioxidants such as N -acetylcysteine and ascorbic acid or over-expression of antioxidant enzymes like superoxide dismutase, can potentially neutralize the toxic effects of MDMA [27, 34]
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