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Ulcerative colitis: signaling pathways, therapeutic targets and interventional strategies | Signal Transduction and Targeted Therapy
In addition, the in vitro cytotoxicity studies with human tumor cell lines carrying glioblastoma, lung, and ovarian carcinoma confirmed that paclitaxel’s activity was maintained in the conjugate ANG1005 where the conjugate was up to 2–3 fold more cytotoxic (2–3 fold lower IC 50 ) towards some cell lines compared to paclitaxel
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