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This contributes to the occurrence of l-dopa-related complications (LDRCs), notably motor fluctuations and l-dopa-induced dyskinesia, whose severity is associated with nigral denervation 2,3,4,5,6,7,8,9
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To confirm whether the lipolytic action of AOD 9604 might merely be associated with the increased lipolytic receptor levels, additional studies were carried out where AOD 9604 was given to mice with knocked out lipolytic receptors
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