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For example, IDH2 mutations drive D -2HG formation, impair D2HGDH, and disrupt PHD/EGLN activity, thereby stabilizing HIF-1α and creating a pseudo-hypoxic state ( D -2HG concentrations ( L -2HG over L -MAL
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Balancing privacy and progress: a review of privacy challenges, systemic oversight, and patient perceptions in ai-driven healthcare
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