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OS is defined as an imbalance between the levels of reactive oxygen species (ROS) and the levels of antioxidant systems, where ROS are in excess.3–7 Sources of reactive oxygen species Levels of ROS may be increased due to its production by endogenous and exogenous sources

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doi: 10.1016/j.smim.2004.08.022 121 RooseJPMollenauerMHoMKurosakiTWeissA