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Figure 1 from Depletion of Glutathione during Oxidative Stress and Efficacy of N-Acetyl Cysteine: An Old Drug with New Approaches | Semantic Scholar

Carson and associates identified the enzyme G6PD deficiency in 1956 in an individual who developed hemolytic anemia after taking the antimalarial drug primaquine

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It is already discovered that the number and location of the positively charged groups in the macrocyclic structure play a key role in porphyrin uptake by the target cells and for appreciable 1 O 2 production [38]