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Upon its accumulation and phosphorylation, HIF-1α dimerizes with HIF-β (constitutively expressed nuclear proteins), enters the nucleus, and promotes the transcription of hypoxia response elements (HRE)-containing target genes involved in energy metabolism, erythropoiesis, vascular remodelling, and other processes (Fig

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The inclusion of benzoyl peroxide points to a need for acne-fighting solutions in bodycare