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Ionic strength affects the solubility and stability of many dissolved materials, screens electrostatic interactions, interferes with some assays, and leaves a residue on drying

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These findings together imply that upregulation of Prxs renders motor neurons less susceptible to neurodegeneration, whereas breakdown of this redox system at late disease stages induces neuronal degeneration and accelerates disease progression (Kato et al., 2005)