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Analysis of the gene promoter region has shown an antioxidant response element (ARE) (8), a putative glucocorticoid response element (GRE) (Fig
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Because tesamorelin stimulates GH production, patients receiving glucocorticoid replacement for previously diagnosed hypoadrenalism may require an increase in maintenance or stress doses following initiation of tesamorelin®, particularly in patients treated with cortisone acetate and prednisone because conversion of these drugs to their biologically active metabolites is dependent on the activity of 11βHSD-1
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