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Anti-Ageing
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In particular, microglial secretion of interleukin-1α (IL-1α), tumor necrosis factor-α (TNFα), and complement component 1q (C1q) induces the neurotoxic A1 phenotype of astrocytes, characterized by loss of neuroprotective functions and the promotion of chronic neuroinflammation associated with neurodegenerative diseases progression
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