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Cutaneous manifestations are common in hypothyroid dogs and can include a dull, dry, brittle dog’s coat, bilaterally symmetrical non-pruritic alopecia (often truncal, on the tail resulting in a “rat tail” appearance, or on the bridge of the nose), failure of hair to regrow after clipping (post-clipping alopecia), scaly skin (flaky skin), hyperpigmentation, and skin thickening due to myxedema (accumulation of mucopolysaccharides in the dermis).8 Hypothyroid dogs are also predisposed to recurrent superficial pyoderma and otitis externa due to alterations in skin barrier function and local immune defenses.8 While the primary alopecia is typically non-pruritic, itching can develop if secondary infections occur
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Even if individual peptides appear low risk, stacking adds uncertainty
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