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51 Diseases related to copper dysregulation Given that either Cu deficiency or accumulation exhibit adverse health effect, it is important to note that the inability to maintain Cu balance has been associated with a wide range of pathologic conditions, including MD, WD, neurodegenerative diseases, cancer, and cardiovascular disease

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Patients should be educated about signs and symptoms of potential serious adverse effects, including pancreatitis, gallbladder disease, and severe hypoglycemia if receiving concurrent antidiabetic therapy