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10.54112/bcsrj.v2021i1.55 [DOI] [Google Scholar] 168.Bayan L, Koulivand PH, Gorji A

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In sepsis-induced AKI models, PKM2 inhibition attenuates the activation of NLR family pyrin domain containing 3 (NLRP3) and absent in melanoma 2 (AIM2) inflammasomes, decreases the release of IL-1β, IL-18, and HMGB1 by macrophages, and ultimately improves survival outcomes (Xie et al., 2016)