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Of course, Apo A1 is important in the diagnosis of monogenic disorders such as Familial hypoalphalipoproteinaemia, Tangier disease, LCAT deficiency (familial LCAT deficiency and Fish Eye disease) and hyperalphalipoproteinaemia due to CETP deficiency, hepatic lipase deficiency, endothelial lipase deficiency or loss of function mutations in scavenger receptor, class B type 1 (SRB1)
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