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The synthesis of GSH from glutamate, cysteine, and glycine involves two steps, catalyzed by glutamate cysteine ligase (also referred to as γ-glutamylcysteine synthetase) and GSH synthetase, respectively, as shown below: 1
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During the children’s transition to adulthood after suffering from radiotherapy, they also need GH treatment to maximize their bone mineral density and prevent osteoporosis (Murray et al., 1999
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