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The Role of Hepatic SIRT1: From Metabolic Regulation to Immune Modulation and Multi-target Therapeutic Strategies
Figure 1 NAD + Treatment Enhances the GSH/GSSG Ratio and Total Glutathione Levels by Increasing Both GCL Levels and Nrf2 Activity of PC12 Cells GCL is the key enzyme for GSH synthesis (Dickinson and Forman, + treatment can increase the total glutathione levels has suggested that the GCL activity may be increased in the NAD + -treated cells
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[DOI] [PubMed] [Google Scholar] Merabet N, Bellien J, Glevarec E, Nicol L, Lucas D, Remy-Jouet I, Bounoure F, Dreano Y, Wecker D, Thuillez C, Mulder P
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