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GHRH receptor agonism → adenylate cyclase activation Elevated cyclic AMP → growth hormone synthesis and pulsatile release Preserved feedback loop → somatostatin and IGF-1 regulation retained Hepatic GH receptor engagement → insulin-like growth factor 1 elevation Adipocyte lipolytic signaling → visceral adipose endpoints in study models Core Areas of Scientific Investigation Visceral Adipose Tissue Research: the compound is the reference GHRH analogue in studies measuring visceral adipose tissue area by computed tomography
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