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Ultimately, integrating epigenetic biomarkers with clinical data may enable clinicians to identify patients with steroid-resistant inflammation driven by an “epigenetic lock” and to tailor adjunctive treatments that specifically target those molecular pathways
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We believe that a better understanding of the molecular mechanisms that result in mitochondrial impairment and oxidative stress together with the regulation of adaptive UPR and autophagy responses will provide the key pieces of information that will unlock novel drug treatments for BD beyond mood stabilizers and antipsychotics
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