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Overview | Vitamin B12 deficiency in over 16s: diagnosis and management | Guidance | NICE

In contrast, recent studies report VB12 inhibits mTOR phosphorylation to induce autophagy in disease models 95

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The 12 mg dose produced 28.3% average body weight loss at 80 weeks, and a higher-BMI two-year subgroup reached 30.3% average loss at 104 weeks