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Therefore, the damage of the oligodendrocytes and demyelinization was considered the consequence of the infiltration of inflammatory cells and activation of the inflammatory process (Figure 2)
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5 Disruption of the neuroendocrine network and the local biochemical microenvironment The pathological microenvironment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) involves not only inflammatory-immune crosstalk and oxidative stress, but alterations in local biochemical components and dysregulation of the neuroendocrine network also represent crucial links in the impairment of sperm development
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