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This inactivation disrupts key enzymatic reactions, including the conversion of methylmalonyl-CoA to succinyl-CoA by methylmalonyl-CoA mutase and the synthesis of methionine from homocysteine (Hcy) by methionine synthase (Figure 2)
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[ 146 ] Similarly, miR‐30c‐5p has been shown to improve myocardial I/R injury by activating NRF2 and inhibiting BACH1
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