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Influence of Proton Pump Inhibitor Treatment on Helicobacter pylori Stool Antigen Test
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The Fh8 presents two EF-hand motifs, and it was characterized as a Ca 2+ sensor protein : when calcium binds, the Fh8 switches from a closed (apo-state) to an open (calcium-loaded state) conformation due to the reorientation of the four helices, exposing a large hydrophobic region that acts as a target-binding surface (Fraga et al., 2010)
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