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Furthermore, in these cases, the development of IgA nephropathy could be speculated due to an elevated response of immune cells in the germinal center, leading to massive antibody production and increased production of pathogenic IgA similar to immunization with the influenza vaccine

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Neuroimaging studies also confirmed similar patterns: sleep-deprived brains show reduced glucose metabolism (the body's process for creating glucose energy in the blood) in regions critical for alertness and attentional control