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*Correspondence: Rosa Zaragozá, [email protected] This article was submitted to Membrane Physiology and Membrane Biophysics, a section of the journal Frontiers in Physiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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DNA methylation typically takes place at cytosine residues within CpG dinucleotides, leading to the formation of 5-methylcytosine (5-mC), with 60% to 90% of these CpG sites being methylated in the mammalian genome