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Notably, the side chain of Lys8 showed a large movement in the structural superposition of reduced and oxidized OsDHAR structures and formed a hydrogen bond (distance = 3.1 Γ ) with the side-chain oxygen of Cys20-sulfonic acid (Figs
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11 Vice versa, it is likely that if cytoprotective agents induce the innate counteraction of the initial Robert-lesions (alcohol, NSAIDs) in the stomach, the same agent exhibits an alike counteraction of the other lesions regularly induced by alcohol and NSAIDs (i.e., in liver, brain)
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