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Through an enhanced study design, it was discovered that antioxidant supplementation led to a reduction in the overall level of mitochondrial biogenesis, while still permitting the induction of mitochondrial biogenesis induced by endurance training
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Only GlyNAC supplementation in OA lowered plasma 8-OHdG by 57% after 2-weeks, and by 73% after 16-weeks (Table 3), and significantly lowered muscle pH2AX after 16-weeks (Figure 2A and B)
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