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Therefore, any pathological event that interferes with mitochondrial structure, transport, density distribution, or metabolic flexibility may trigger structural and network-level amplification effects in the nervous system, manifested as synaptic failure, axonal degeneration, and even neuronal death
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Therefore, we next examined whether the cytoprotective effects of MAPKAPK2 under oxidative stress are dependent on its kinase activity by using a selective MK2 pharmacological inhibitor (PF-3644022)
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