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Very little is known about the effect of cytokines on neuronal excitability, however, IL-6 has been shown to reduce group-II metabotropic glutamate receptors and L-type calcium channels.[236] In fact, IL-6 has been found in some studies to offer significant neuroprotection against calcium overload by reducing NMDA receptor activity.[149] This appears to be contradictory to the finding, that of all the cytokines, IL-6 alone was most closely associated with mortality in PD patients.[72] Baseline levels of IL-6 were higher in patients who died during the 4-year follow-up period and along with age, these represent two independent factors related to the risk of mortality in PD patients

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Weight:1 lbs

Entering 2026, several emerging trends are reshaping how providers approach peptide protocols, compliance, and patient care