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Novel cell line models to study mechanisms and overcoming strategies of proteasome inhibitor resistance in multiple myeloma
Lactic Acid
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EZH2i increased genes related to FA mobilization from cellular stores such as ATGL, responsible for triacylglycerol (TAG) catabolism whose activity could be prevented by the concomitant upregulation of its inhibitor G0S2, potentially explaining the increased LDs content
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