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In addition, the presence of AΞ² peptide also affects the action of NβmethylβDβaspartate (NMDA) receptors [182], leading to new protein synthesis, dendritic spine formation [183], and glutamate homeostasis disorders, which in turn cause structural and functional abnormalities and excitability toxicity of nerve cells
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The first step in glutamine utilization is its conversion to glutamate by glutaminase (GLS)
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