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Being such small and stable molecules, they have been widely used in biomedical applications, and due to their versatility, they have raised the possibility of their use in future innovative applications, which makes them new promises in biotherapy ( The main function of proangiogenic peptides is being a mimetic signal that can be recognized by the receptors of growth factors that trigger the formation of blood vessels ( in vitro and in vivo assays, such as QK, RoY, LL-37, PBA2-1c, Exendin-4, Peptide derivatives of Osteonectin (OPD, SPARC113, and SPARC118) and Peptide derivative of osteopontin (OPD), in this section we will include those that have been used to bio functionalize HGs

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