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JCI Insight - Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π
19,24 This latter function of TRIF signaling involves activation of an E3 ubiquitin ligase, Peli1, which conjugates lysine 63-linked ubiquitin chains to RIP1, thereby facilitating the recruitment and activation of IKK
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