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Moreover, genetic studies show that GRK gene variants are associated with essential hypertension, blood pressure response to antihypertensive medicines, and adverse cardiovascular outcomes of antihypertensive treatment
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Although the genetic variations in the genes of astrocytes or microglia have not been reported, the knockdown of chemokine receptor 1 ( CX3CR1 ) resulted in a reduction in microglia, ASD-associated functional connectivity, and behavioral deficits and defects in synaptic pruning [200, 201]
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