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Early animal studies suggest its potential to slow or reverse fibrosis, offering hope for more effective treatments

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the antibody comprises a V H comprising a sequence set forth in SEQ ID NO: 42 and a V L comprising a sequence set forth in SEQ ID NO: 46, wherein the V H and/or V L comprise one or more of the following substitutions or groups of substitutions: the V H comprises an alanine at position 16 of SEQ ID NO: 42