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In humans, two studies in AD patients have supported the positive cognitive effects of LA (Hager et al., 2001, Many studies reported beneficial effects of LA in the rat brain or neuronal cell cultures, using different molecular markers of oxidative stress, such as reduction in the levels of lipid peroxides and protein carbonyls, recycling endogenous antioxidants such as vitamin C and E, increasing glutathione levels (Packer et al., 1997
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